Journal of nanobiotechnology
NGO ameliorates psoriasis by modulating mitochondrial function and suppressing pSTAT3-IL-17-expressing CD8+ TRM cells.
Tae Ho Kim, Chae Rim Lee, Kyoung Min Choi, Soon Won Choi, Seon-Yeong Lee, A Ram Lee, Jung Won Choi, Young Mi Moon, Joonhyuck Park, Haeyoun Choi, Jaechul Ryu, Chul Hwan Bang, Mi-La Cho
Published: 202610.1186/s12951-025-04020-7
Abstract
Psoriasis is a chronic autoimmune skin disorder characterized by keratinocyte hyperproliferation, persistent inflammation, and frequent relapse. Tissue-resident memory T (TRM) cells, particularly IL-17- and phosphorylated STAT3 (pSTAT3)-expressing CD…
Preview only. Read the full abstract at the source