Journal of nanobiotechnology
Engineered neutrophil membrane nanosystem for targeted siRNA therapy in myocardial ischemia-reperfusion injury.
Yaohui Jiang, Zhe Wang, Penglei Chen, He Lu, Xiaoxu Tian, Pin Jiang, Rui Luo, Yujing Zhou, Zhikang Lv, Wenjun Mao, Shuai Ren, Xiaocheng Wang, Haiqiang Sang, Wei Yang
Published: 202510.1186/s12951-025-03965-z
Abstract
Despite the widespread use of emergency coronary reperfusion therapy, effectively managing reperfusion-induced myocardial injury remains a major clinical challenge. Neutrophil infiltration and the release of damage-associated molecular patterns (DAMP…
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