Journal of inflammation (London, England)
Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors.
Marco De Zuani, Petra Lázničková, Marcela Hortová Kohoutková, Veronika Bosáková, Ivana Andrejčinová, Natália Vadovičová, Veronika Tomášková, Alexandra Mýtniková, Julie Štíchová, Tomáš Tomáš, Jiří Hrdý, Kristýna Boráková, Stjepan Uldrijan, Marcela Vlková, Vladimír Šrámek
Published: 202610.1186/s12950-025-00483-5
Abstract
BACKGROUND: Sepsis is a life-threatening condition characterised by an overwhelming immune response and high fatality. While most research has focused on its acute phase, many sepsis survivors remain immunologically weakened leaving them susceptible…
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