Respiratory research
Modulation of an aberrant basal cell program in human alveolar epithelial spheroids and lung slices subtitle: modulating aberrant basal cells in human cells and tissues.
Yong Li, Jack H Wellmerling, Lorena Rosas, Patrick A Link, Daniela Chow, Joshua Alvarez, Kyoung M Choi, Ana M Diaz Espinosa, Rachel M Gilbert, Nicholas P Goplen, Donghao Li, Andrew J Haak, Y S Prakash, Mauricio Rojas, Daniel J Tschumperlin
Published: 202510.1186/s12931-025-03441-0
Abstract
RATIONALE: Idiopathic Pulmonary Fibrosis (IPF) is a progressive scarring disease marked by the accumulation of aberrant basal cells that are thought to promote disease progression. The cellular origin and disease-relevant cues that lead to aberrant b…
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