BMC biology
IbinA and IbinB regulate the Toll pathway-mediated immune response in Drosophila melanogaster.
Matthew K Maasdorp, Susanna Valanne, Laura Vesala, Petra Vornanen, Elina Haukkavaara, Tea Tuomela, Aino Malin, Tiina S Salminen, Dan Hultmark, Mika Rämet
Published: 202610.1186/s12915-025-02501-7
Abstract
BACKGROUND: To combat infection, an immune system needs to be promptly activated but tightly controlled to avoid destruction of host tissues. IbinA and IbinB are related short peptides with robust expression upon microbial challenge in Drosophila mel…
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