BMC complementary medicine and therapies
Implications of notoginsenoside R1 in osteoclastogenesis and bone remodeling via nitric oxide modulation.
Jia-Feng Chen, Chih-Chieh Chen, Wan-Ling Lin, Tun-Pin Hsueh
Published: 202610.1186/s12906-026-05264-y
Abstract
BACKGROUND: Bone remodeling depends on the balance between osteoblast-mediated formation and osteoclast-mediated resorption, with disruption contributing to osteoporosis and other osteolytic diseases. Nitric oxide (NO) serves as a critical regulator…
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