BMC cancer
Comprehensive pan-cancer characterization of IRAK2 as a potential prognostic biomarker and therapeutic target with validation in hepatocellular carcinoma.
HaiJian Dong, Yuanqian Yao, Qun Niu, Xueqing Gong, Yu Mou, Zijian Zeng, Hui Li
Published: 202510.1186/s12885-025-15474-1
Abstract
BACKGROUND: Inflammation plays a critical role in cancer initiation and progression by modulating the tumor microenvironment and immune responses. Interleukin-1 receptor-associated kinase 2 (IRAK2) is a key mediator of the Toll-like receptor and inte…
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