BMC gastroenterology
mRNA expression of NLRP3 and IL1B in inflammatory bowel diseases: a systematic review and meta-analysis.
Paula I Metselaar, Roos C H Schilder, Aletta D Kraneveld, Anje A Te Velde, Andrew Y F Li Yim
Published: 202510.1186/s12876-025-04566-8
Abstract
BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the gastrointestinal tract. Clinical studies of IBD robustly show elevated interleukin 1β (IL-1β) levels in intestinal tissue, implicating the NLR family pyrin domai…
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