BMC microbiology
Comparative metagenomic characterization of gut microbiota and antibiotic resistome in multi-facility SPF mice.
Yujie Wang, Caihong Wu, Qi Zhu, Chun Fan, Yingying Zhu, Yifei Chen, Xiaofeng Wei, Liping Feng
Published: 202610.1186/s12866-025-04699-6
Abstract
Specific pathogen-free (SPF) mice are pivotal preclinical models linking basic microbiology to clinical translation, yet comprehensive high-resolution profiling of their gut microbiome, especially antibiotic resistance genes (ARGs), remains limited.…
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