BMC bioinformatics
MGANSL: multi-network representation generating with generative adversarial network for synthetic lethality prediction.
Jinxin Li, Xinguo Lu, Zihao Li, Xing Liu, Hongrui Liu, Jingjing Ruan
Published: 202510.1186/s12859-025-06345-4
Abstract
BACKGROUND: Cancer is a complex disease that arises from the simultaneous mutations of multiple biological molecules. An effective therapeutic strategy is to exploit synthetic lethality (SL) by targeting the SL partner of cancer driver genes. Computa…
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