Cellular & molecular biology letters
TGFβ pathway represses hepatic ribosome biogenesis and protein synthesis by regulating p70S6K-S6RP proteins.
Athanasios Stavropoulos, Vassiliki Stamatopoulou, Eleftherios Pavlos, Maria Manioudaki, Stratigoula Sakellariou, Constantinos Stathopoulos, Maria Xilouri
Published: 202610.1186/s11658-025-00853-0
Abstract
BACKGROUND: Transforming growth factor-beta (TGFβ)-superfamily signaling has been implicated in the regulation of hepatocyte growth and regeneration after acute or chronic liver injury. However, the precise mechanisms underlying TGFβ signaling in the…
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