The European respiratory journal
A European multi-center, randomized controlled trial of Pirfenidone in bronchiolitis obliterans syndrome after bilateral lung transplantation.
Michael Perch, Paul Corris, Jim Lordan, Vasiliki Bessa, Jesper Magnusson, Geert M Verleden, Robin Vos, Nikolaus Kneidinger, Inga Leuckfeld, Erik Verschuuren, Jens Gottlieb
Published: 202510.1183/13993003.02154-2024
Abstract
BACKGROUND: Chronic Lung Allograft Dysfunction (CLAD) is a major obstacle to improving outcomes after lung transplantation. Bronchiolitis Obliterans Syndrome (BOS), characterized by progressive decline in FEV1 due to fibrotic scarring of the small ai…
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