Blood advances
HMB-002: A Monovalent Antibody that Elevates Circulating VWF and FVIII Levels for Treatment of Von Willebrand Disease.
Mattias Häger, Minka Zivkovic, Prafull S Gandhi, Caroline Rasmussen, Cécile Bonvoisin, Rane A Harrison, Emil Poulsen, Dana Huskens, Mark Roest, Fortunato Ferrara, Anais Naretto, Lionel Renaud, Ole H Olsen, Nicolas O Eskesen, Lars Holten-Andersen
Published: 202610.1182/bloodadvances.2025018516
Abstract
Von Willebrand Disease (VWD) is the most common inherited bleeding disorder, resulting from deficiency or dysfunction of von Willebrand Factor (VWF), a protein crucial for hemostasis. Current prophylactic options present significant limitations inclu…
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