Blood advances
Humoral and cellular immune response after COVID-19 vaccination in patients with sickle cell disease on hydroxyurea.
Sabine Haggenburg, Cilia R Pothast, Quincy Hofsink, Nienke J E Haverkate, Michel S Bhoekhan, Mathieu Claireaux, Rob S van Binnendijk, Gerco den Hartog, Birgit I Lissenberg-Witte, Rory D de Vries, Charlotte F J Van Tuijn, Bart J Biemond, Erfan Nur, Corine GeurtsvanKessel, Pim G N J Mutsaers
Published: 202510.1182/bloodadvances.2025017239
Abstract
Patients with sickle cell disease (SCD) are at increased risk of COVID-19-related mortality compared to healthy individuals, also after vaccination. To what extent impaired vaccine-induced immunity contributes to this risk is unknown. We prospectivel…
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