Blood
Von Willebrand Factor Deficiency Impairs Angiogenesis via Angiopoietin-2: Relevance for Gut Angiodysplasia.
Adela Constantinescu-Bercu, Koval E Smith, Shuo Yi Wong, Mattia Ballerini, Alessia Nastro, Benjamin G Wiggins, Daniela Pirri, Yucheng Li, Juun Anora Maria Evers, Olga Tsiamita, Matthew Dibble, Charis Pericleous, Koralia E Paschalaki, Graeme M Birdsey, Jeremiah Bernier-Latmani
Published: 202610.1182/blood.2025031558
Abstract
Management of recurrent gastrointestinal (GI) bleeding is a clinical unmet need for patients with Von Willebrand disease (VWD) and is linked to the presence of gut vascular malformations (angiodysplasia). We previously demonstrated that von Willebran…
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