Blood
Time of Day of CAR T-Cell Infusion and Outcomes in Large B-Cell Lymphoma.
Danny Luan, Ori Ben Valid, Ofrat Beyar-Katz, Tobias Tix, Noa Golan-Accav, Mohammad Alhomoud, Abraham Avigdor, Veit L Bücklein, Limor Cohen, Parastoo B Dahi, Sigrun Einarsdottir, Julia Elimelech, Silvia Escribano Serrat, Lorenzo Falchi, Teng Fei
Published: 202510.1182/blood.2025031476
Abstract
Circadian rhythms orchestrate immune activation and effector function, yet whether within-day timing influences chimeric antigen receptor (CAR) T-cell therapy outcomes remains unknown. We conducted an international, multicenter retrospective study of…
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