Blood
Increased Prevalence of Clonal Hematopoiesis in Children with Sickle Cell Disease.
Jessica Ulloa, Kristin Wuichet, Sara R Rashkin, Yash Pershad, Connor Shore, Caitlyn Vlasschaert, Mark J Rodeghier, Yu Yao, Victor R Gordeuk, Binal N Shah, Clifford M Takemoto, Santosh L Saraf, Michael R DeBaun, Mitchell J Weiss, Alexander G Bick
Published: 202510.1182/blood.2025030898
Abstract
Recent studies have reached opposing conclusions about whether clonal hematopoiesis (CH) is increased or decreased in patients with sickle cell disease (SCD). Given that CH is typically age-related, its presence in children with SCD could offer uniqu…
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