Blood
Selective Depletion of ABO-Responsive B Cells by T-Cell-Engaging Bispecific Antibody Conjugates for ABOi Transplantation.
Hyeong Ryeol Choi, Honglin Piao, Shafrizal Rasyid Atriardi, In Kang, Tae Kyung Chang, Serin Kim, Joon Young Jang, Gwangmin Lee, Kyeong Cheon Jung, Hanifah Mardhiyah, Fazsa Islamianti Machmud, Jin Park, Sang Kook Woo, Jaeseok Yang, Chan Hyuk Kim
Published: 202610.1182/blood.2025030660
Abstract
Organ transplantation is a pivotal treatment for patients with organ failure. ABO-incompatible (ABOi) transplantation, developed to expand the donor pool, presents significant clinical challenges due to pre-existing antibodies targeting ABO antigens…
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