BloodHumansMiddle AgedAdultPrecursor Cell Lymphoblastic Leukemia-LymphomaAged
Impact of TP53 mutations and their variant allele frequency in adults with newly diagnosed acute lymphoblastic leukemia.
Roberta S Azevedo, Elias Jabbour, Hagop M Kantarjian, Sravanthi Lavu, Sanam Loghavi, Nitin Jain, Koji Sasaki, Rebecca S Garris, Koichi Takahashi, Farhad Ravandi, Nicholas J Short
Published: 202610.1182/blood.2025030498
Abstract
ABSTRACT: TP53 mutations are associated with unfavorable survival in many hematologic malignancies. However, the impact of TP53 mutations and their variant allele frequency (VAF) in acute lymphoblastic leukemia (ALL) remains unclear. We retrospective…
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