BloodHematopoietic Stem CellsMethylationProtein BiosynthesisMiceAnimals
Dynamic rRNA methylation regulates translation in the hematopoietic system and is essential for stem cell fitness.
Ofri Rabany, Sivan Ben Dror, Maram Arafat, Hadar Aharoni Levitanus, Yudit Halperin, Virginie Marchand, Nikolai Romanovski, Noga Ussishkin, Maayan Livneh Golany, Adi Reches, Judith Wexler, Nina Mayorek, Galia Monderer-Rothkoff, Sagiv Shifman, Widad Mâmmer Bouhou
Published: 202610.1182/blood.2024028300
Abstract
ABSTRACT: Self-renewal and differentiation are at the basis of hematopoiesis. Although it is known that tight regulation of translation is vital for hematopoietic stem cells' (HSC) biology, the mechanisms underlying translation regulation across the…
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