Blood
Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI).
Enrico Attardi, Nathan Gray, Sara Lewis, Michelle Eubanks Boals, Passant Shaker, Lili Kotmayer, Sushree S Sahoo, Peng Li, Erica F Andersen, Jian Zhao, Lucilla Pizzo, Joseph H Oved, Rohith Jesudas, Ulrike M Reiss, Richa Sharma
Published: 202510.1182/blood.2024028042
Abstract
We evaluated 108 pediatric patients with bone marrow failure and leukemia predisposition for presence of clonal hematopoiesis in peripheral blood (PB) and bone marrow (BM). We found robust PB-BM concordance for mutations but decreased sensitivity in…
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