The CRISPR journal
BAR-CAT: Targeted Recovery of Synthetic Genes via Barcode-Directed CRISPR-dCas9 Enrichment.
Natanya K Villegas, Mindy H Tran, Abigail Keller, Calin Plesa
Published: 202510.1177/25731599251401526
Abstract
Modern gene synthesis platforms enable investigations of protein function and genome biology at an unprecedented scale. Yet, the proportion of error-free constructs in diverse gene libraries decreases with length due to the propagation of oligo synth…
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