Journal of neuromuscular diseases
Translational behavioral phenotypes in DMSXL mice for CNS manifestations of DM1.
Elisabetta Golini, Aline Huguet-Lachon, Hélène Benyamine, Noëmy Forasté Gueriba, Ferdinando Scavizzi, Marcello Raspa, Germana Falcone, Beatrice Cardinali, Silvia Mandillo, Geneviève Gourdon
Published: 202610.1177/22143602251410998
Abstract
BACKGROUND: Myotonic dystrophy type 1 (DM1) is a multisystemic disorder frequently associated with central nervous system (CNS) involvement, especially in congenital and childhood-onset forms. However, behavioral alterations in preclinical models hav…
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