Omics : a journal of integrative biology
Immune-Suppressed, Not Immune-Cold: HMOX1-CD14-Immunoproteasome Axis and Structure-Guided Combination Pharmacotherapies in Isocitrate Dehydrogenase-Mutant Glioblastoma.
Sezin Gürkan Şali, Şeyma Çolakoğlu Özkaya, Betül Budak, Şükrü Güllüoğlu, Cevdet Nacar, Ömer Faruk Bayrak, Kazım Yalçın Arga, Ahmet İlter Güney
Published: 202510.1177/15578100251408286
Abstract
Glioblastoma (GBM) remains one of the most aggressive human malignancies, and its biological diversity is largely shaped by the isocitrate dehydrogenase (IDH) mutation status. Although apoptosis, autophagy, and ferroptosis have each been implicated i…
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