Journal of Alzheimer's disease : JAD
The role of HDAC6-mediated Prx2 acetylation in neuronal apoptosis related to Alzheimer's disease.
Lijie Zhang, Jinxia Hu, Tao Zhang, Huimin Gao, Xingrui Wu, Conghui Zhang, Cheng Zhang, Hao Chen, Minggang Yang, Xichuan Cao, Guiyun Cui, Jie Xiang
Published: 202610.1177/13872877251414961
Abstract
BackgroundThe role of histone deacetylase 6 (HDAC6) in neurodegenerative diseases, particularly Alzheimer's disease (AD), has attracted significant research interest. Peroxiredoxin 2 (Prx2), a key antioxidant enzyme and HDAC6 substrate, plays a neuro…
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