Epigenomic aberrations of histone methylation in prefrontal cortex of humans with mild cognitive impairment and Alzheimer's disease.

BackgroundEpigenetic mechanisms, particularly histone modifications at gene promoters, are crucial for controlling gene transcription.ObjectiveWe aim to find out epigenomic aberrations during the progression of neurodegenerative disorders.MethodsWe e…

Preview only. Read the full abstract at the source