Journal of Alzheimer's disease : JAD
Microglial transcriptional profiles of a transgenic rat model closely model Alzheimer's disease.
Carrie J Finno, Sharmila Ghosh, Veronika Rodriguez, Anthony Valenzuela, Peter Andrew, Heui Hye Park, Ana Cristina Grodzki, Nathifa Nasim, Kelsey Roberts, Blythe Durbin-Johnson, Ken A Jackson, Patricia A Pesavento, Pamela J Lein
Published: 202610.1177/13872877251410206
Abstract
Single-cell RNA-sequencing has identified that Alzheimer's disease (AD) pathology in humans is associated with activation of disease-associated microglia (DAM). Microglial signatures of human AD have not been consistently identified in AD mouse model…
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