Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
The Role of EP3 Agonism in Intraocular Pressure-Lowering by Sepetaprost, a Novel Dual Agonist of FP and EP3 Receptors, in Monkeys.
Kentaro Maki, Erika Kimura, Yasuko Yamamoto, Masahiro Fuwa, Carol B Toris, Shan Fan, Atsushi Shimazaki, Masatomo Kato
Published: 202510.1177/10807683251401740
Abstract
Purpose: This study aimed to elucidate the contribution of EP3 receptor agonism to the intraocular pressure (IOP)-lowering effects of sepetaprost, a novel dual agonist of FP and EP3 receptors, in monkeys. Methods: The agonistic activities of ONO-AG-3…
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