Human & experimental toxicologyAnimalsLipopolysaccharidesOxidative StressFemaleMice
Inhibition of store-operated calcium entry mitigates lipopolysaccharide-induced hepatotoxicity via modulating inflammatory and oxidative stress responses.
Mohammed Alqinyah, Abdullah S Alhamed, Yasseen A Alassmrry, Mohamed Mohany, Khaldoon Aljerian, Khalid Alhazzani, Mohammad M Algahtani, Hussain N Alhamami, Ahmed Z Alanazi, Faris Almutairi
Published: 202610.1177/09603271251411659
Abstract
IntroductionHepatotoxicity can arise secondary to several medical conditions, including inflammation, sepsis, and therapy. Lipopolysaccharide (LPS) can activate diverse inflammatory pathways and has been implicated in hepatotoxicity. The store-operat…
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