Veterinary pathology
A comprehensive review of humanized mice applications in regulatory submissions for cell and gene therapy products.
Giovanni Pellegrini, Lucia Minoli, Sara Degl'Innocenti, Michela Gabaldo, Valeria Bertani, Alessandra Piersigilli, Francesca Sanvito, Patrizia Cristofori
Published: 202610.1177/03009858251411297
Abstract
The emergence of cell and gene therapies has transformed the therapeutic landscape, offering curative potential for a range of previously intractable diseases. However, their biological complexity and patient-specific mechanisms of action present sig…
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