Veterinary pathology
Artificial intelligence predicts c-KIT exon 11 genotype by phenotype in canine cutaneous mast cell tumors: Can human observers learn it?
Chloé Puget, Jonathan Ganz, Christof A Bertram, Thomas Conrad, Malte Baeblich, Anne Voss, Katharina Landmann, Alexander F H Haake, Andreas Spree, Svenja Hartung, Leonore Aeschlimann, Sara Soto, Simone de Brot, Martina Dettwiler, Heike Aupperle-Lellbach
Published: 202510.1177/03009858251380284
Abstract
Canine cutaneous mast cell tumors (ccMCTs) are frequent neoplasms with variable biological behaviors. Internal tandem duplication mutations in c-KIT exon 11 (c-KIT-11-ITD) are associated with poor prognosis but predict therapeutic response to tyrosin…
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