A Streptozotocin-Induced Mouse Model of Renal Tumors: Histopathological and Immunohistochemical Comparisons With Human Chromophobe Renal Cell Carcinoma.

Streptozotocin (STZ) is known to induce renal tumors in rodents, but their similarity to human tumors remains poorly defined. We characterized and comparatively validated a mouse model of STZ-induced renal tumorigenesis by administering a single intr…

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