Ear, nose, & throat journal
A Comprehensive Review of the PENTOCLO Protocol and Its Applications in the Head and Neck.
Salena Ringenbach, Shriya Airen, Jarrod Keeler, Ravi Samy, Chetan Nayak, Jason F Ohlstein
Published: 202510.1177/01455613251381176
Abstract
OBJECTIVE: To evaluate the clinical use of pentoxifylline and tocopherol (PENTO), with or without clodronate (PENTOCLO), in the treatment and prevention of osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ). METHODS: A l…
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