SRY-Box Transcription Factor 18 Links Inflammation to Calcific Aortic Valve Progression via CD68 and NF-κB p65.

This study investigated SOX18's role in calcific aortic valve disease (CAVD). Aortic valve specimens from 67 patients undergoing valve replacement were stratified into control (n = 18), mild (n = 20), and severe calcification (n = 29) groups based on…

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