The American journal of psychiatryHumansImpulsive BehaviorGenome-Wide Association StudyGenetic PleiotropyMale
Characterizing the Pleiotropic Architecture of Impulsivity and Its Links to Psychopathology and Neurodevelopment.
Travis T Mallard, Justin D Tubbs, Mariela Jennings, Yingzhe Zhang, Daniel E Gustavson, Andrew D Grotzinger, Margaret L Westwater, Camille M Williams, Rebecca G Fortgang, Sarah L Elson, Pierre Fontanillas, Lea K Davis, Armin Raznahan, Elliot M Tucker-Drob, Karmel W Choi
Published: 202610.1176/appi.ajp.20240382
Abstract
OBJECTIVE: Impulsivity is a complex mental construct and a core feature of many psychiatric and neurological conditions. The aim of this study was to formally model the genetic architecture of eight impulsive traits, identifying their shared and dist…
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