JCI insightHumansFemaleHerpes GenitalisHerpesvirus 2Human
Genital herpes shedding episodes associate with altered spatial organization and activation of mucosal immune cells.
Finn MacLean, Rachael M Zemek, Adino Tesfahun Tsegaye, Jessica B Graham, Jessica L Swarts, Sarah C Vick, Nicole B Potchen, Irene Cruz Talavera, Lakshmi Warrier, Julien Dubrulle, Lena K Schroeder, Anna Elz, David Sowerby, Ayumi Saito, Katherine K Thomas
Published: 202610.1172/jci.insight.197491
Abstract
Herpes Simplex Virus 2 (HSV-2) infection results in variable rates of local viral shedding in anogenital skin. The effect of episodic viral exposures on immune cells in adjacent mucosal tissues, including the genital tract, is unknown. However, any i…
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