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LAIR1 prevents excess inflammatory tissue damage in Staphylococcus aureus skin infection and Cutaneous T-cell Lymphoma.
Hannah K Dorando, Evan C Mutic, Kelly L Tomaszewski, Yulia Korshunova, Ling Tian, Mellisa K Stefanov, Chaz C Quinn, Deborah J Veis, Juliane Bubeck Wardenburg, Amy C Musiek, Neha Mehta-Shah, Jacqueline E Payton
Published: 202510.1172/jci.insight.183935
Abstract
Patients with cutaneous T cell lymphoma (CTCL) experience high morbidity and mortality due to S. aureus skin infections and sepsis, but the underlying mechanisms remain unclear. We have previously identified high levels of LAIR2, a decoy protein for…
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