The Journal of clinical investigationHumansRNATransferSchizophreniaOlfactory Mucosa
Elevated tRNA halves in olfactory epithelial cells of patients with schizophrenia.
Justin T Gumas, Megumi Shigematsu, Karin E Borgmann-Winter, Chang-Gyu Hahn, Yohei Kirino
Published: 202610.1172/JCI195148
Abstract
Open AccessSchizophrenia patients' olfactory epithelial cells contain abundant immune-activating tRNA fragments, linking small RNA biology to inflammation and suggesting avenues for diagnostics.