The Journal of clinical investigationHumansHypereosinophilic SyndromeMaleT-LymphocytesFemale
Cellular profiling identifies targetable T cell phenotypes in lymphocytic variant hypereosinophilic syndrome.
Kristy Tefft, Amy Wang, Zachary Z Reinstein, Yue Zhang, Arundhati Pillai, Sunghee Hwang, Spencer Ng, Raymond J Cho, Jeffrey B Cheng, Fei Li Kuang, Brett King, Jaehyuk Choi
Published: 202510.1172/JCI190853
Abstract
Open AccessWith cell-by-cell mapping, we charted immune cells in lymphocytic-variant hypereosinophilic syndrome, found drug targets, and showed targeted therapy removed disease-causing cells and eased symptoms.