Translational vision science & technologyAnimalsGenetic TherapyRabbitsDependovirusCorneal Diseases
Long-Term Tolerability and Safety of AAV5-Id3 Gene Therapy to Eyes.
Suneel Gupta, Rajnish Kumar, Nishant R Sinha, Lynn M Martin, Prashant R Sinha, Frederick W Fraunfelder, Alexandria C Hofmann, Nathan P Hesemann, Rajiv R Mohan
Published: 202610.1167/tvst.15.1.38
Abstract
Purpose: The inhibitor of differentiation 3 gene therapy via adeno-associated virus 5 (AAV5-Id3) effectively abrogated corneal fibrosis in vivo. This study examined the long-term tolerability and safety of AAV5-Id3 gene therapy for eyes in vivo using…
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