Investigative ophthalmology & visual scienceAnimalsFuchs' Endothelial DystrophyCollagen Type VIIIMiceDisease Models
Early Transcriptomic and Pathologic Changes of Col8a2 Mutant Fuchs Endothelial Corneal Dystrophy.
Xintian Zhao, Haoyun Duan, Shengqian Dou, Xiaoyu Li, Yujing Lin, Can Zhao, Dongfang Li, Libo Zhou, Zongyi Li, Qingjun Zhou
Published: 202610.1167/iovs.67.1.53
Abstract
Purpose: The purpose of this study was to characterize the early transcriptomic and pathologic changes of Fuchs endothelial corneal dystrophy (FECD) using the Col8a2Q455K/Q455K mutant mouse model. Methods: The Col8a2Q455K/Q455K mutant mice were divid…
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