American journal of respiratory cell and molecular biology
SART3 Activates CD36 Transcription by Recruiting FOXM1 and Activates PARP to Augment Cisplatin Resistance in Non-Small Cell Lung Cancer.
Wenhui Huang, Bin Bi, Qilan Huang, Haijing Wu, Xinghan Cheng, Li Pan
Published: 202510.1165/rcmb.2025-0319OC
Abstract
Cisplatin resistance remains a major barrier to effective lung cancer treatment. In this study, we identified that SART3 is upregulated in cisplatin-resistant non-small cell lung cancer (NSCLC) cells and promotes DNA damage repair. SART3 deletion sen…
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