American journal of respiratory and critical care medicine
Transcriptomic Profiling in Mycobacterium avium Complex Pulmonary Disease Identifies Clusters Linked to Disease Severity and Neutrophil Activation.
Chio Sakai, Mizu Nonaka, Masashi Matsuyama, Sosuke Matsumura, Masayuki Nakajima, Kodai Ueda, Naoki Arai, Yuko Morishima, Masafumi Muratani, Yukio Ishii, Takefumi Saito, Nobuyuki Hizawa
Published: 202510.1164/rccm.202503-0665OC
Abstract
RATIONALE: Mycobacterium avium complex (MAC) pulmonary disease presents with heterogeneous clinical phenotypes. OBJECTIVES: This study aimed to elucidate the heterogeneity of MAC pulmonary disease by analyzing gene expression profiles in whole blood…
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