Journal of the American Heart AssociationDNAMitochondrialAnimalsHumansHeart Arrest
Mitochondrial DNA-Mediated Immune Activation After Resuscitation From Cardiac Arrest.
Tyler J Rolland, Emily R Hudson, Luke A Graser, Sumbule Zahra, Daniel Cucinotta, Swati D Sonkawade, Umesh C Sharma, Brian R Weil
Published: 202610.1161/JAHA.125.046414
Abstract
BACKGROUND: Postcardiac arrest syndrome is characterized by systemic inflammation that contributes to poor outcomes after resuscitation from sudden cardiac arrest. Mitochondrial DNA (mtDNA) has been implicated as a proinflammatory stimulus in other c…
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