Journal of the American Heart Association
C-C Chemokine Receptor 4 Deficiency Protects Against Abdominal Aortic Aneurysm Formation.
Aga Krisnanda, Naoto Sasaki, Toru Tanaka, Ken Ito, Takuo Emoto, Takeshi Yoshida, Hilman Zulkifli Amin, Sayo Horibe, Gusty Rizky Teguh Ryanto, Noriaki Emoto, Tomoya Yamashita, Ken-Ichi Hirata, Kazuhiko Matsuo, Takashi Nakayama, Yoshiyuki Rikitake
Published: 202510.1161/JAHA.125.043202
Abstract
BACKGROUND: The dysregulated immune system, which drives chronic vascular inflammation and remodeling, plays a critical role in the pathogenesis of abdominal aortic aneurysm (AAA). CCR4 (C-C chemokine receptor 4), which is predominantly expressed on…
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