Arteriosclerosis, thrombosis, and vascular biology
Whole-Body Knockout of the AhR (Aryl Hydrocarbon Receptor) Ameliorates Atherosclerosis Due to Altered Lipid Metabolism.
Rosanna Huchzermeier, Renske J de Jong, Leonida Rakateli, Andrea Bonnin-Marquez, Sanne L Maas, Chantal Maassen-Pöttgens, Kathrin Abschlag, Han Jin, Anna-Lena Geiselhöringer, Vasiliki Triantafyllidou, Donato Santovito, Joachim Jankowski, Erik A L Biessen, Caspar Ohnmacht, Emiel P C van der Vorst
Published: 202610.1161/ATVBAHA.125.323673
Abstract
BACKGROUND: Atherosclerotic cardiovascular disease, characterized by an imbalanced lipid metabolism and a dysregulated immune response, is a major cause of death worldwide. The AhR (aryl hydrocarbon receptor) is a ligand-activated transcription facto…
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