Multisystem inflammatory syndrome in children associated with COVID-19: a case report and literature review.
Mohamedraza Akbar Ebrahim, Shadrack Elia Makundi, Noureen Ndelimbi Mushi, Pendo Mussa Ibrahim, Rukhsar Shabir Osman, Zainab Fidaali, Deogratias Arnold Nkya
Abstract
Open AccessGiven the rarity of multisystem inflammatory syndrome related to COVID-19 (MIS-C). This case report highlights the high index of suspicion to diagnose MIS-C in a child who presented with symptoms suggestive of acute gastroenteritis. While admitted in the hospital, she deteriorated with worsening of symptoms, clinical decline, deranged laboratory markers, and significant radiological findings, even though on antibiotics. She had acute myocarditis with myocardial dysfunction on echocardiography and raised cardiac enzymes. Intravenous human immunoglobulin (IVIG) was given, but there was additional need for inotrope (norepinephrine) and methylprednisolone albeit the preliminary echocardiogram was normal. Early recognition of MIS-C with rapid escalation of care post IVIG administration is needed to prevent morbidity and mortality.