Concurrent Wilms Tumor and Severe Dilated Cardiomyopathy in an Infant Requiring Veno-Arterial Extracorporeal Membrane Oxygenation.

Introduction: The combination of Wilms tumor (WT) and severe dilated cardiomyopathy (DCM) in infants is a rare occurrence, as is the need for advanced life support with extracorporeal membrane oxygenation (ECMO). Case Presentation: We present a 3-month-old infant with concurrent WT and severe DCM, which required complex management, including urgent veno-arterial (VA) ECMO support and neoadjuvant chemotherapy prior to resection. Conclusion: This case underscores the exceptional nature of managing an infant with concurrent WT and DCM, highlighting the need for tailored, multidisciplinary approaches. The use of ECMO, neoadjuvant chemotherapy, and careful surgical planning facilitated the successful management of this complex pediatric patient.