Cancer immunology research
IL-10R inhibition induces neutrophil tumoricidal activity.
Danny N Khalil, Ricardo Gomez, Amit Regev, Fadi Samaan, Yacine Marouf, Sadna Budhu, Daniel Hirschhorn, Isabell Schulze, Jessica A Lavery, Nicholas Ceglia, Samuel S Freeman, Vivien I Maltez, Jaynia M Garcia, Nathan Suek, Chien-Huan Weng
Published: 202610.1158/2326-6066.CIR-25-0834
Abstract
While the role of neutrophils in modulating antitumor T cell responses has been extensively studied, their direct effects on tumor cells remains less well understood. In this study, we investigated whether neutrophils have the capacity to directly ki…
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