Cancer immunology research
TCPGdb: A comprehensive T cell perturbation genomics database for identification of critical T cell regulators.
Chuanpeng Dong, Feifei Zhang, Kaiyuan Tang, Nipun Verma, Xinxin Zhu, Di Feng, James Cai, Hongyu Zhao, Sidi Chen
Published: 202510.1158/2326-6066.CIR-25-0168
Abstract
Large parallel genetic screens have been used to identified targets and regulators that enhance T cell antitumor capability and persistence in tumor microenvironment. We hypothesized that by combining the pooled screen data from multiple independent…
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